产品货号：
Z24708
中文名称：
PYGL抗体
英文名称：
Anti-PYGL Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PYGL Antibody |
| 指标别名 | PYGL;Glycogen phosphorylase,liver form |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,FCM(Intracellular),Direct ELISA |
| 基因名称 | PYGL |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human PYGL recombinant protein (Position:K313-K804). |
| 实际分子量 | 97KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Glycogen phosphorylase,liver form (PYGL),also known as human liver glycogen phosphorylase (HLGP),is an enzyme that in humans is encoded by the PYGL gene on chromosome 14.This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores.This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15.Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls.Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver,brain and muscle,respectively.The liver isozyme serves the glycemic demands of the body in general while the brain and muscle isozymes supply just those tissues.In glycogen storage disease type VI,also known as Hers disease,mutations in liver glycogen phosphorylase inhibit the conversion of glycogen to glucose and results in moderate hypoglycemia,mild ketosis,growth retardation and hepatomegaly.Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Uniprot ID | P06737 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | glycogen phosphorylase L |
| 蛋白名全称 | Glycogen phosphorylase,liver form |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Flow Cytometry(Intracellular) 1～3μg/1×106 cells Direct ELISA 1:100～1000 |
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